Department of Crop Sciences
Gustavo Caetano-Anolles
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Gustavo Caetano-Anolles

Professor
332 National Soybean Res Ctr
1101 West Peabody Drive
Urbana, IL 61801
(217) 333-8172

Research Areas

Interaction of plants and microbes
The spontaneous mutation process
Evolution of biological networks
Function and structure in proteins and ncRNA
Evolution of macromolecular structure

Journal Articles

Nasir A, A Naeem, MJ Kahn, HD Lopez Nicora and G Caetano-Anollés (2011) Annotation of protein domains reveals remarkable conservation in the functional make up of proteomes across superkingdoms. Genes 2:869-911.(pdf)

Wang M, CG Kurland and G Caetano-Anollés (2011) Reductive evolution of proteomes and protein structures. Proceedings of the National Academy of Sciences USA 108: 11954-11958.(abstract) (pdf)

Kim KM and G Caetano-Anollés (2011) The proteomic complexity and rise of the primordial ancestor of diversified life. BMC Evolutionary Biology 11:140 (abstract) (pdf)

Caetano-Anollés D, KM Kim and G Caetano-Anollés (2011) Proteome evolution and the metabolic origins of translation and cellular life. Journal of Molecular Evolution 72: 14-32. 

Wang M, YY Jiang, KM Kim, G Qu, HF Ji, JE Mittenthal, HY Zhang and G Caetano-Anollés (2011) A universal molecular clock of protein folds and its power in tracing the early history of aerobic metabolism and planet oxygenation. Molecular Biology and Evolution 28: 567-582 (abstract)

Twizeyimana M, PS Ojiambo, JS Haudenshield, G Caetano-Anollés, KF Pedeley, R Bandyopadhyay and GL Hartman (2011) Genetic structure and diversity of Phakopsora pachyrhizi isolates from soyabean. Plant Pathology 60:719-729.

Qi M, F-J Sun, G Caetano-Anollés, and Y Zhao (2010) Comparative genomic and phylogenetic analysis of two-component signal transduction systems in Erwinia amylovora and related enterobacteria. Journal of Molecular Evolution 70:167-180 (abstract)

Sun F-J and G Caetano-Anollés (2010) The ancient history of the structure of ribonuclease P and the early origins of Archaea. BMC Bioinformatics 11:153 (abstract)

Kim KM and G Caetano-Anollés (2010) Emergence and evolution of modern molecular functions inferred from phylogenomic analysis of ontological data. Molecular Biology and Evolution 27 (7): 1710-1733 (abstract)

Dupont CL, A Butcher, RE Valas, PE Bourne, and G Caetano-Anollés (2010) History of biological metal utilization inferred through phylogenomic analysis of protein structure. Proceedings of the National Academy of Sciences USA 107 (23): 10567-10572 (abstract)

Sun F-J and G Caetano-Anollés (2010) The origin of modern 5S rRNA: A case of relating models of structural history to phylogenetic data. Journal of Molecular Evolution 71(1): 3-5 (abstract)

Caetano-Anollés D, KM Kim and G Caetano-Anollés (2010) Proteome evolution and the metabolic origins of translation and cellular life. Journal of Molecular Evolution 72: 14-32 (abstract)

Caetano-Anollés G, and JE Mittenthal (2010) Exploring the interplay of stability and function in protein evolution. BioEssays 32(8): 655-658 (abstract)

Caetano-Anollés G, M Wang, D Caetano-Anollés, and JE Mittenthal (2009) The origin, evolution and structure of the protein world. Biochemical Journal 417: 621-637 (abstract)(pdf).

Caetano-Anollés G, LS Yafremava, H Gee, D Caetano-Anollés, and JE Mittenthal (2009) The origin and evolution of modern metabolism. International J Biochemistry & Cell Biology 41: 285-297. (abstract)(advance access: pdf)

Sun F-J and G Caetano-Anollés (2009) The evolutionary history of the structure of 5S ribosomal RNA. Journal of Molecular Evolution 69:430-443 (abstract).

Sun F-J and G Caetano-Anollés (2009) The evolutionary significance of the long variable arm in transfer RNA. Complexity14:26-39 (abstract).

Wang M and G Caetano-Anollés (2009) The evolutionary mechanics of domain organization in proteomes and the rise of moduarity in the protein world. Structure 17: 66-78 (abstract) Press release: Study of protein structures reveals key events in evolutionary history

Sun F-J and G Caetano-Anollés (2008) Transfer RNA and the origins of diversified life. Science Progress 91: 265-284. (abstract)

Caetano-Anollés G, Sun F-J, ML, Wang, LS Yafremava, A Harish, HS Kim, V Knudsen, D. Caetano-Anollés G and JE Mittenthal (2008) Origins and evolution of modern biochemistry: insights from genomes and molecular structure. Frontiers in Bioscience 13: 5212-5240. (abstract)(pdf)

Kim KM, S Sung, G Caetano-Anollés, JY Han, and H Kim (2008) An approach to orthology detection from homologous sequences under minimum evolution. Nucleic Acids Research 36(17): e10 (abstract) (pdf)

Sun F-J and G Caetano-Anollés (2008) Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code. PLoS ONE 3: e2799 (abstract)(pdf) Press release: Study reveals surprising details of the evolution of protein translation

Sun F-J and G Caetano-Anollés (2008) Evolutionary patterns in the sequence and structure of transfer RNA: early origins of Archaea and viruses. PLoS Computational Biology 4: e1000018. (abstract) (pdf) Press release: Researchers see history of life in the structure of transfer RNA

Knudsen V and G Caetano-Anollés (2008) NOBAI: a web server for character coding of geometrical and statistical features in RNA structure. Nucleic Acids Research 36: 85-90 (abstract)(pdf)

Sun F-J and G Caetano-Anollés (2008) The origin and evolution of tRNA inferred from phylogenetic analysis of structure. Journal of Molecular Evolution 66: 21-35. (abstract)

Caetano-Anollés G, HS Kim and JE Mittenthal (2007) The origin of modern metabolic networks inferred from phylogenomic analysis of protein architecture. Proceedings of the National Academy of Sciences USA 104: 9358-9363. 

Wang M, LS Yafremava, D Caetano-Anollés, JE Mittenthal and G Caetano-Anollés (2007) Reductive evolution of architectural repertoires in proteomes and the birth of the tripartite world. Genome Research 17: 1572-1585. 

Sun F-J, S Fleurdepine, C Bousquet-Antonelli, G Caetano-Anollés and J-M Deragon (2007) Common evolutionary trends for tRNA-derived SINE RNA structures. Trends in Genetics 23: 26-33.

Martin N, EA Ruedi, R LeDuc, F Sun and G Caetano-Anollés (2007) Gene-interleaving patterns of synteny in the Saccharomyces cerevisiae genome: Are they proof of an ancient genome duplication event? Biology Direct 2: 23. 

Books

Caetano-Anollés G (2010) Evolutionary Genomics and Systems Biology. Wiley-Blackwell (ad).
Caetano-Anollés G and PM Gresshoff (1997) DNA markers: Protocols, Applications and Overviews. John Wiley & Sons, Inc., New York.